CD4+ Count
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Test Overview
A CD4+ count is a blood test to determine how well the immune system is working in people who have been diagnosed with human immunodeficiency virus (HIV). CD4+ cells are a type of white blood cell. White blood cells are important in fighting infections. CD4+ cells are also called T-lymphocytes, T-cells, or T-helper cells.
HIV infects CD4+ cells. The number of CD4+ cells helps determine whether other infections (opportunistic infections) may occur. The pattern of CD4+ counts over time is more important than any single CD4+ value because the values can change from day to day. The CD4+ pattern over time shows the effect of the virus on the immune system. In people infected with HIV who are not getting treated, CD4+ counts generally decrease as HIV progresses. A low CD4+ count usually indicates a weakened immune system and a higher chance of getting opportunistic infections.
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| Last updated: | March 01, 2007 |
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| Author: | Maria G. Essig, MS, ELS |
| Reviewed By: | E. Gregory Thompson, MD - Internal Medicine, Peter Shalit, MD, PhD - Internal Medicine |
| Editors: | Susan Van Houten, RN, BSN, MBA, Tracy Landauer |
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