Retinoid (tretinoin) cream for warts


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Brand Name Chemical Name
Retin-Atretinoin

How It Works


Tretinoin is derived from vitamin A, one of a class of substances called retinoids. Retinoid cream disrupts the wart's skin cell growth. Follow your health professional's instructions for applying it at home.


Why It Is Used


Retinoids are commonly used to treat acne and aging skin.


How Well It Works


In one small study (two groups of 25 subjects), 85% of the children treated with tretinoin cream were successfully cleared of warts, compared with only 32% of those treated with a placebo.1


Side Effects


Oral use of retinoid medication is linked with serious birth defects. Tretinoin cream is therefore not recommended for pregnant women.

When applied to the skin, tretinoin cream can cause:

  • Dry, irritated skin.
  • Changes in skin color.
  • Sunlight sensitivity (requiring sunscreen use or covering of treated skin).
  • Red, swollen, crusted, or blistered skin.

Overuse of tretinoin cream can increase skin irritation without improving treatment results.

See Drug Reference for a full list of side effects. (Drug Reference is not available in all systems.)


What To Think About


Tretinoin safety data for children and breast-feeding women is not well established.

Tretinoin treatment of women who are or could be pregnant is not recommended.

Do not use tretinoin cream in combination with another topical treatment, such as salicylic acid, as significant skin irritation can result.

Complete the new medication information form (PDF) (What is a PDF document?) to help you understand this medication.


References


Citations

  1. Sterling JC, et al. (2001). Guidelines for the management of cutaneous warts. British Journal of Dermatology, 144(1): 4–11.


Credits


Author Sabra L. Katz-Wise
Author Ralph Poore
Editor Susan Van Houten, RN, BSN, MBA
Associate Editor Pat Truman
Primary Medical Reviewer Adam Husney, MD

- Family Medicine
Primary Medical Reviewer Kathleen Romito, MD

- Family Medicine
Specialist Medical Reviewer Randall D. Burr, MD

- Dermatology
Last Updated October 20, 2006

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Last updated: October 20, 2006
Author: Ralph Poore
Reviewed By: Kathleen Romito, MD - Family Medicine, Randall D. Burr, MD - Dermatology
Editors: Susan Van Houten, RN, BSN, MBA, Pat Truman

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