Expectorants for chronic obstructive pulmonary disease (COPD)


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Examples


Prescription expectorants

Brand Name Chemical Name
Sinumist-SR Capsuletsguaifenesin
Brand Name Chemical Name
R-Geniodinated glycerol

Nonprescription expectorants

Brand Name Chemical Name
Halotussinguaifenesin

Guaifenesin is available in tablet, capsule, or liquid form. Iodinated glycerol is available in liquid form. Your health professional will help you decide which form is best for you.


How It Works


Expectorants may keep mucus from sticking to the airways of the lungs, making it easier to cough up. They are no longer commonly used.


Why It Is Used


Expectorants may be used in chronic obstructive pulmonary disease (COPD) when it is difficult to cough up mucus from the lungs. However, expectorants are not commonly recommended for COPD treatment.1


How Well It Works


Expectorants may bring some relief from symptoms, but there is no evidence that they improve lung function.2


Side Effects


Some people who use guaifenesin experience nausea, vomiting, dizziness, rash, and itching.

Some people who use iodinated glycerol develop a rash. In rare cases, people who use this medication for long periods of time may develop an underactive thyroid gland (hypothyroidism).

See Drug Reference for a full list of side effects. (Drug Reference is not available in all systems.)


What To Think About


The best way to reduce development of mucus is to stop smoking.

Complete the new medication information form (PDF) (What is a PDF document?) to help you understand this medication.


References


Citations

  1. Global Initiative for Chronic Obstructive Lung Disease (GOLD) (2005). Executive summary (updated 2005). In Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease. Available online: http://www.goldcopd.com/GuidelinesResources.asp?I1=2&I2=0.

  2. Barnes PJ (2000). Nonantimicrobial aspects of therapy. Seminars in Respiratory Infections, 15(1): 52–58.


Credits


Author Lila Havens
Author Robin Parks, MS
Editor Kathleen M. Ariss, MS
Editor Katy E. Magee, MA
Associate Editor Michele Cronen
Associate Editor Tracy Landauer
Associate Editor Pat Truman
Primary Medical Reviewer Renée M. Crichlow, MD

- Family Medicine
Primary Medical Reviewer Kathleen Romito, MD

- Family Medicine
Specialist Medical Reviewer Ken Y. Yoneda, MD

- Pulmonology
Last Updated June 16, 2006

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Last updated: June 16, 2006
Author: Robin Parks, MS
Reviewed By: Kathleen Romito, MD - Family Medicine, Ken Y. Yoneda, MD - Pulmonology
Editors: Katy E. Magee, MA, Pat Truman

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